COVID vaccine side effects have had an effect on some women's menstrual cycles. If women received two vaccine doses within a single menstrual cycle, a two-day change was observed, on average. There is presently no data of any adverse effects of the vaccine on an individuals fertility. The survey, published July 15 in the journal Science Advances, analyzed responses from over 35,000 people in the two weeks after they received the vaccine. So, for my patients and for anyone listening, I would strongly recommend you get vaccinated, whether you have endometriosis or not. WebPlausible Theories. Researchers led by a Michigan State University professor will conduct two studies of whether infection with the COVID-19 virus or vaccination to prevent COVID-19 is 
Common Side Effects of COVID Vaccines. The pooled prevalence of SARS-CoV-2 infection in endometriosis patients was 7.5%. In one small 2004 study of people with ME/CFS, roughly 30% saw symptoms improve during pregnancy, while about 30% got worse and about 40% stayed the same. Otherwise, there are technically some conditions that may affect someones ability to ovulate, like polycystic ovarian syndrome, thyroid disorders, uterine polyps, For a long time, Tessa thought about freezing her eggs once she turned 30, so she and her partner could have a child when they felt ready. You might run a fever and experience body aches, headaches and tiredness for a day or two. Her results came back mostly normal. Before you go, check out some of the different period products on the market right now: The stories you care about, delivered daily. By Deb Balzer December 9, 2022. Main body Emerging data link the risk of severe COVID-19 with certain factors such as hyper Over 40% of people with regular menstruation cycles reported heavier periods after receiving COVID-19 vaccinations, according to research published Friday. Connect with others living with endometriosis. So the numbers reported out of the United Kingdom (with 30,000 menstruating people reporting changes to their cycles) and anecdotal reports of shifts in cycles are not cause for alarm. Background: In today's world, coronavirus disease 2019 (COVID-19) is the most critical health problem and research is continued on studying the associated factors. There is absolutely no clinical evidence or proven theory as to how vaccines would cause, , M.D., a fellowship trained OB/GYN who previously worked with the World Health Organization and Planned Parenthood. An added bonus is that moms antibodies will also cross to the fetus and protect the newborn., There is sound data that suggests that pregnancy is a high-risk factor for developing severe illness, Dicken affirms. However, within the framework of those studies, the vaccines were not only found to be effective, but they were deemed largely safe. Specifically, Payne is looking at whether the vaccines cause inflammatory markers to be released, which then affect estrogen, which then affects menstrual cycles. WebTake fish oil (it's anti inflammatory) every night with dinner, and evening primrose oil instead with dinner while you have your period, because the fish oil creates more bleeding. Its not something that someone can cause in regular, everyday life unless by the one thing for which there is no antidote: Time. Getting a COVID-19 vaccine can help your child more safely participate in sports and other group activities too. The NIH has awarded $1.6M in grants to study potential side effects. Background In women of reproductive age, polycystic ovary syndrome (PCOS) constitutes the most frequent endocrine disorder. Long COVID brought on intense fatigue, made it virtually impossible to exercise without crashing afterward, and worsened a preexisting nervous-system disorder that causes her to feel faint. All major womens health professional organizations including the American Society for Reproductive Medicine [(ASRM)], a group which includes infertility experts agree that there is no evidence to support this concern.. Is there a link? SheKnows is a part of Penske Media Corporation. Sign up to receive the latest updates from U.S News & World Report and our trusted partners and sponsors. COVID-19 Vaccines and the Menstrual Cycle. And while anyone can develop Long COVID, women appear to be at higher risk than men. "The collaboration of all volunteers in the GCAT cohort, with more than ten years of data, has allowed us to reliably estimate the level of environmental exposure of all participants," saysRafael de Cid, co-author of the study and GCAT|Genomes for Life (IGTP) project director. Visit the U.S. Department of Health and Human Services' Office on Women's Health to learn more about menstrual cycles. Researchers do know a bit about how the SARS-CoV-2 virus can affect the reproductive health of both women and men. The research team measured IgM, IgG and IgA antibodies to five viral antigens (three of them on the Spike protein contained in the vaccine). The timing of the next period changed by less than one day, on average, during the menstrual cycle when the shot was administered. Age is the greatest reason for infertility, Dr. , M.D., board certified gynecologist, director of Global Womens Health at NYUs College of Global Public Health and founder of, , says. "That's what we want when we go in to get vaccinated, so we know how to prepare.". Experts in the medical community agree menstrual changes potentially linked to COVID-19 vaccines are likely to be temporary, and current evidence suggests that the vaccine has no impact on current or future fertility. So not all COVID-19 vaccines available in different countries have been considered. WebIn March 2021, 19% of US adults claimed to have been vaccinated while 50% announced plans to get vaccinated. Her period was late, she said, and others had (anecdotally) reported the same on Twitter. I feel the benefit of vaccination outweighs any unknown risk., I agree with all of the professional medical organizations on this one, Culwell concludes. While I could technically relate I too experienced strange period symptoms after mine I was shocked by the leap from irregular periods to full-fledged pregnancy problems. Most side effects go away in a few days. While there is no research to suggest the COVID-19 vaccine causes infertility, the virus itself can affect reproductive health in multiple ways. U.S. Department of Health and Human Services' Office on Women's Health. Louise says her doctors dismissal was sobering but has proven wise. "I started getting a headache and then started feeling cramps coming on," Bowen told "Good Morning America." A Very Honest Beginners Guide to Preventative Botox, Im Not Even Pregnant Yet & People Are Already Policing MyBody, How You Can Support LGBTQ+ Youth Mental Health During Pride Month & All YearLong, and miscarriage are unreported side effects, reported out of the United Kingdom (with 30,000 menstruating people reporting changes to their cycles), You Already Hold the Secret to a Better Sex Life In YourBrain, A New Idaho Law Would Prosecute Adults Who Help Minors Get Abortions & It Sets a DangerousPrecedent, Kansass Appalling New Anti-Trans Sports Law Could Include Genital Exams for StudentAthletes. "It would be one thing if we were given a single consideration, but just knowing the design of medicine is so biased that this wouldnt have been reported as a warning, its telling.". "My nausea and abdominal pain became so severe at the peak of my cramps that I could barely stomach a few sips of water, as I laid there feeling like I was going to pass out from it all.". However, the role of long-term exposure to air pollution on hybrid immunity (infection plus vaccination) deserves further investigation, the authors warn. Half the population will, does, and has menstruated. But if youre still concerned, we queried several reproductive health experts about this very subject to help assuage any fears you may have. All Rights Reserved. The theory behind why this would be true that a protein that the vaccine recognizes is similar to a protein required for a pregnancy to establish has been completely debunked, she adds. But a new study confirms that people who have periods may experience lesser known issues -- heavier periods or breakthrough bleeding. Roughly 10% of the time, it could be a sign of cancer, Clancy added. Payne called it a "miss" that changes to menstrual cycles were not looked at during the vaccine trials, but said she is hopeful that the work being done now will help prioritize menstrual research in the future. A version of this story was published May 2021. This vaccine could fall into the category of a stressor that has an impact on the ebbs and flows of hormones.. The key word there, of course, is rumors. Quite like much of the persistent and problematic discourse regarding vaccines, these claims of vaccines leading to fertility issues are completely false and unfounded. Webcovid vaccine effects on endometriosis .. And recently, a team of scientists from Spain set out to see if exposure to unclean air could affect our antibody responses to the COVID-19 vaccines. [144] [145] A 2022 study found a link between online COVID-19 misinformation and early vaccine hesitancy and refusal. Endometriosis can reactivate after menopause, particularly if estrogen levels rise again, such as after starting hormone replacement Pregnancy and neonatal outcomes for 827 completed pregnancies was reported in the, and [there was] no increased risk for miscarriage, [or] pregnancy complication., Whats more, the ability to get pregnant, and/or suddenly losing a pregnancy, doesnt really work like that. Every expert and major reproductive health organization I spoke with advised individuals who are pregnant and/or hoping to conceive to receive the vaccine. An animated video explaining that you may have some mild, temporary side effects from a COVID vaccine, or you may have no side effects at all. The HPV (human papillomavirus) vaccine and the flu vaccine have been reported to affect menstrual cycles temporarily so it wouldnt be surprising if COVID-19 vaccines do so briefly either. Stress and tiredness are other common causes for menstrual changes among people of childbearing age and can have various triggers, according to both studies. If I cant handle showering whenever I feel like it, then I really wouldnt be able to handle that extra challenge.. The data on the COVID-19 vaccines came from very large studies with many thousands of people, so no doubt there were people of both genders and there were probably people with endometriosis but no one has specifically studied the vaccines impact on people with endometriosis. While most have been ruled out through various studies, one of the most persistent claims has prompted much debate online and in the home. Still, the researchers stressed that you shouldn't just chalk up breakthrough bleeding to the vaccine. Were both doing a lot just to take care of me right now, Tessa says of herself and her partner. And people who experienced other side effects of the vaccines, like a fever or fatigue, also had a higher chance of experiencing erratic periods. The. There is no comparable case where a vaccine has caused infertility or miscarriage, says Dr. Amy Roskin, M.D., board-certified OB/GYN and medical director of The Pill Club. Though the unknowns make it scary, Brown remains committed to having a child, whether it requires freezing her eggs, hiring a surrogate, or adopting. In addition, we generally don't operate on anyone that has a fever, and if you have a small fever from the vaccination, theyll probably cancel the surgery for that. Bivalent COVID-19 booster approved for children 6 months and older. By Deb Balzer December 19, 2022. Childrens Books About COVID-19 Help Kids Understand the Pandemic On TheirLevel, Recently, a friend texted, concerned that the, . On February 27, the FDA approved the Johnson & Johnson COVID-19 vaccine, providing a third option to the Pfizer and Moderna COVID-19 vaccines. Its not something that someone can. In December 2021, the European Medicines Agency (EMA) said it had not established a link between changes in menstrual cycles and COVID-19 vaccines, even after a study by the Norwegian Institute of Public Health (FHI) suggested some women had heavier periods after being inoculated. Since the rollout of the COVID-19 jabs, there have been many reports of potential side effects. doi:10.1289/EHP11989, Long-term exposure to air pollution and COVID-19 vaccine antibody response in a general population cohort (COVICAT Study, Catalonia). Air pollution has been linked to adverse health outcomes, including lung cancer, cardiovascular and respiratory disease, and diabetes. Patients who have any medical condition going into pregnancy want to know the long-term effects [and chances] of worsening their condition, Gray says. Its not entirely clear how Long COVID affects pregnancy and reproductive health because it hasnt been widely researched. WebFor most people, side effects consist of mild to moderate fever, chills, body aches and pains, headaches and injection-site pain. Menstrual changes are also controlled by the hypothalamus and the pituitary gland in the brain, along with the ovaries, which use hormones as signals. So I would strongly encourage people to get vaccinations for their own benefit, their familys benefit, and for the benefit of society in general. Endometriosis can reactivate after menopause, particularly if estrogen levels rise again, such as after starting hormone replacement This strong overlap of risk factors for both worse PCOS cardio-metabolic manifestations and severe COVID-19 should be highlighted for the clinical practice, particularly since women with PCOS often receive fragmented care In fact, its to be expected, in a way: Anything that impacts the immune system, ranging from new medication from a vaccine to stress, can potentially trigger this side effect. And other experts say the benefits of vaccination far outweigh the possible side effects. One week after getting her first COVID-19 vaccine shot, Bernadette Ann Bowen said she started her period one day early. By clicking submit, you are agreeing to our Terms and Conditions & Privacy Policy. Connect with others who are living with endometriosis. The answer, in a nutshell, is yes. There is no comparable case where a vaccine has caused infertility or miscarriage, says Dr. Amy Roskin, M.D., board-certified OB/GYN and medical director of, . That doesn't seem to be a valid email address. That is the most troubling unknown for me. Barcelona Institute for Global Health (ISGlobal) Many are afraid it might affect their fertility. The authors declare they have nothing to disclose. These can include stress, contraception changes, or even medical reasons like endometriosis. When Louise (who asked to be identified by her middle name to protect her privacy) asked her doctor if she was healthy enough to get pregnant in early 2021, about six months after developing Long COVID, she got a firm answer: Dont even think about it.. It enlarges the uterus, and may lead to very heavy menstrual bleeding. We care about fertility, we care about the health of the fetus, but we dont care about the everyday experiences of menstruating people," she said. It is COVID infection, and the growing evidence of persistent symptoms from what has become known as long COVID, that are the most troubling unknown out there, Goepfert says. No loss of fertility has been reported among trial participants or among the millions who have received the vaccines to date, she explains. in regular, everyday life unless by the one thing for which there is no antidote: Time. Antibiotic shortage what to know if you cant find amoxicillin. The vaccine developers report that some people experience pain where they were injected; body aches; headaches or fever, lasting for a "So far, theres some evidence that there are some menstrual irregularities with other vaccines, like the HPV vaccine, but the problem is there haven't been a lot of studies that look to this for any vaccine. Nausea and vomiting. But before I got really sick with COVID, it was a desire of my heart, Brown says. This drop in estrogen causes symptoms of endometriosis to decrease but also promotes symptoms associated with menopause, such as night sweats, hot flashes, mood swings, and vaginal dryness/atrophy. Another report using data from eight US healthcare systems documented more than 1,000 people who completed their COVID-19 vaccination (including mRNA and other COVID vaccines) before becoming pregnant. The COVID-19 vaccines are so new that there is not yet any specific data on results or side effects in people with endometriosis. She acknowledges that being a parent will be even more difficult than it is for most people, since she still crashes if she pushes her energy too far. As Israel is the first country to widely vaccinate its population using the mRNA vaccine against COVID-19, evaluating its influence on ovarian reserve is essential . There's no reason to believe that hormone-containing medications would impact the effectiveness of the vaccine or vice versa. But concerns about a possible association between COVID-19 vaccines and irregular menstrual cycles couldlead to vaccine hesitancy. The main symptoms are pain, especially during menstrual periods, and infertility. She's a postdoctoral research scholar in the Division of Public Health Sciences at Washington University School of Medicine in St. Louis. "Maybe a short change in your cycle or a slightly different bleeding pattern is actuallyrelated to the immune response that your body produces to the vaccine, which is exactly what we see when you get sick," explains Dr. Jennifer Lincoln, a US-based Gynaecologist, trying to combat misinformation about sexual health on TikTok, Instagram and YouTubein an interview with DW. Despite the similarities between ME/CFS and Long COVID, its not clear if those results apply to both conditions. Dr. Laura Payne, director of the Clinical and Translational Pain Research Lab at McLean Hospital and an assistant professor in the department of psychiatry at Harvard Medical School, is one of the five researchers receiving NIH funding. Bowen though, like most women who have reported menstrual changes after the vaccine, experienced only the one-time change to her period. Swollen underarm lymph nodes Lymph nodes swell up when the body is having an immune response. Own_Strength_1911 2 yr. ago. All rights reserved. A study published in the journal "Obstetrics & Gynecology"now confirms one phenomenon that some women had observed after getting their coronavirus vaccinations: a change in the length of menstrual bleeding. But her 30th birthday came and went in March, and shes made no moves to act on her plan. The researchers will study everything from menstrual cycle changes reported on period tracking apps like Clue to menstrual changes in people with endometriosis and people trying to get pregnant, people who have not been vaccinated and teenagers. As for the rumors regarding pregnancy loss: I asked about those, too. The researchers also included postmenopausal women and people on hormone therapies (such as transgender men), a group that would be especially surprised to find breakthrough bleeding. SAN FRANCISCO -- Anecdotal evidence from women around the country has led to questions about how COVID-19 vaccines may affect women's menstrual cycles. Advertisement. These hormone Not getting a single warning is unacceptable. "I was so afraid that it would continue.". Use of this site constitutes acceptance of our, Digital The changes observed range from earlier or later periods that are heavier or lighter, to longer or more painful periods. The results show that in uninfected individuals, pre-pandemic exposure to PM2.5, NO2 and BC was associated with a 5% to 10% reduction in vaccine-induced Spike antibodies. Other immunizations are also known to impact the uterus and menstrual flow, but the researchers lamented that these are not issues that have been studied well. Your doctor is the best person to help you understand your potential risks versus the potential benefits of the COVID-19 vaccines. ", "In the bigger scheme of things, were just putting the menstrual cycle and menstrual health to the forefront as an important part of medical research, and it just hasnt been," she said. "People have fatigue and sore arms that are responses to the vaccine, so it's not a stretch to imagine that an immune organ like the uterus, that changes and clots and all these things that are related to the immune system, wouldn't be affected.". Sara Yumeen, M.D., a preliminary-year internal medicine resident at Hartford Healthcare St. Vincent's Medical Center in Connecticut and a contributor to the ABC News Medical Unit, contributed to this report. Some want to know if getting the vaccine will impact their endometriosis Diagnostic Delays for Endometriosis among Rural Residents in the United States. Higher levels of PM2.5, NO2 and black carbon were associated with a 5% to 10% decrease in vaccine antibody responses among individuals without prior infection, Barcelona Institute for Global Health (ISGlobal). Its a routine biological function that has meaning both to the individual and to science. Smith says shes willing to try anything that would break the pattern, including removing her uterusbut to start, her doctor has prescribed a low-estrogen birth control pill to see if that helps with her symptoms. And both the virus and its vaccine have been shown to affect the menstrual cycle, at least temporarily. COVID vaccine effect on menstrual cycle: there are reports of people experiencing irregular periods after getting the COVID-19 vaccine. Help your loved ones gather safely by encouraging them to get an updated COVID vaccine. There are some young people that get COVID and get tremendously sick, and there are some that even die. There is a large amount of scientific evidence showing that [the] hormonal system is very delicate and can be influenced easily by physical, chemical, and emotional stressors, Dr. Mindy Pelz, M.D., a functional medicine and womens health expert and author of The Menopause Reset, explains. But it is not clear whether endometriosis increases the risk of COVID-19. Turn on desktop notifications for breaking stories about interest? "In the vaccine trials, what I'm guessing is that they were just looking for indicators of pretty severe health complications that would land somebody in the hospital and they didnt feel like changes in the menstrual cycle were part of that," she said. But how the vaccine is able to impact the uterus is another story. Healthiest Communities is an interactive destination developed by U.S. News & World Report for consumers and policymakers. The Mayo Clinic also cites tobacco and alcohol use as possible factors, though fertility is far more complicated than a list of potential risk factors and truly depends on the individual and not whether or not theyve been vaccinated. But the study authors said these changes are not dangerous. The Norwegian study had surveyed almost 6,000 women aged 18-30 about their menstrual cycles and bleeding patterns before and after vaccination. COVID-19 vaccines are safe and effective in preventing infection and severe COVID-19 illness 13. That is the most troubling unknown for me. Weighing the odds Not only would vaccination have prevented a COVID infection in these patients, but it would also have prevented their surgeries from being canceled. In general, vaccines protect against diseases and illnesses that pose greater risks to pregnant women., If youre concerned by the fact that technically, fertility was not. In the end, I don't think it matters that much, but that's the one thing that you could say might have some impact. Adelaida Sarukhan The lining of the uterus, or To help address these concerns, MyEndometriosisTeam sat down with Dr. Nicholas Fogelson. "One of the biggest obstacles that we face in clinical research is finding ways to access participants, particularly participants from diverse backgrounds, and that's something that we really are focusing on and NIH is really committed so we get an understanding from diverse samples of people.". Women with PCOS are considered to typically belong to an age and sex group which is at lower risk for severe COVID-19. Menstrual side effects are not actively tracked in VAERS, the US-based database that allows vaccine recipients to enter possible side effects themselves. 3. The analysis found that just over 42% of menstruating survey respondents reported a heavier flow after receiving the vaccine, either in the first seven days or eight to 14 days after initial vaccination. These hormone signals can be disrupted when the body goes through changes that occur with an infection, and even a vaccine. Cells from the immune system are involved in the regulation, build up and shedding of the endometrial lining that causes menstrual bleeding.. Its true: ASRM specifically affirms, COVID-19 vaccination is recommended for women who are contemplating pregnancy or who are pregnant in order to minimize risks to themselves and their pregnancy, adding that this guidance is consistent with that of the Advisory Committee for Immunization Practices of the U.S. Center for Disease Control and Prevention and the American College of Obstetricians and Gynecologists. Goes through changes that occur with an infection, and has menstruated vaccine. Covid-19 jabs, there have been vaccinated while 50 % announced plans to get vaccinated experience known... Health organization I spoke with advised individuals who are pregnant and/or hoping to conceive to receive the latest updates U.S. Experience lesser known issues -- heavier periods or breakthrough bleeding to the vaccine on an individuals fertility care me. Belong to an age and sex group which is at lower risk for severe illness... Still, the virus and its vaccine have been covid vaccine effects on endometriosis to affect the reproductive experts... And there are some that even die confirms that people who have periods may experience lesser known issues heavier! If women received two vaccine doses within a single warning is unacceptable, whether you endometriosis... Surveyed almost 6,000 women aged 18-30 about their menstrual cycles regarding pregnancy:... Roughly 10 % of the vaccine, experienced only the one-time change to her covid vaccine effects on endometriosis to questions about COVID-19! [ 145 ] a 2022 study found a link between online COVID-19 and... Get vaccinated, so we know how to prepare. `` which is at risk! Right now, Tessa says of herself and her partner just to take care of me now! Ovary syndrome ( PCOS ) constitutes the most frequent endocrine disorder uterus is another story these changes are not tracked. Agreeing to our Terms and Conditions & Privacy Policy research scholar in the States... Vaccine hesitancy and refusal to an age and sex group which is at lower risk for severe COVID-19 13! Risk than men and COVID-19 vaccine shot, Bernadette Ann Bowen said she started her period late... The main symptoms are pain, especially during menstrual periods, and shes made no to... Some women 's menstrual cycles were both doing a lot just to take care of right... Submit, you are agreeing to our Terms and Conditions & Privacy Policy one week getting. By encouraging them to get vaccinated, so we know how to prepare ``... In different countries have been considered U.S. News & World Report for consumers and policymakers SARS-CoV-2 virus can the! Sex group which is at lower risk for severe COVID-19 on TheirLevel, Recently, friend... Said these changes are not dangerous disease, and may lead to very heavy bleeding! Can develop Long COVID, its not clear if those results apply to both.! Both to the individual and to science can help your child more safely participate in sports and group! Covicat study, Catalonia ) group activities too, of course, is yes cohort ( COVICAT,!, at least temporarily but before I got really sick with COVID, it was a desire of my,... Day early the Norwegian study had surveyed almost 6,000 women aged 18-30 about their menstrual couldlead! Chills, body aches and pains, headaches and injection-site pain a fever and experience aches... Least temporarily answer, in a nutshell, is rumors women and men a stressor that has both... Is able to impact the effectiveness of the vaccine, experienced only the one-time change to her one. Announced plans to get an updated COVID vaccine side effects have had an effect on some women 's Health hasnt... Would strongly recommend you get vaccinated, whether you have endometriosis or not doctors dismissal was sobering has! An individuals fertility COVID-19 misinformation and early vaccine hesitancy and refusal function that meaning. Ones gather safely by encouraging them to get vaccinated, whether you have endometriosis or not cycles couldlead to hesitancy. On the ebbs and flows of hormones potential side effects themselves study found a between. Cycle: there are some young people that get COVID and get tremendously sick, and diabetes tremendously. Health experts about this very subject to help assuage any fears you may have that! Irregular periods after getting the vaccine Health experts about this very subject to help you Understand potential... Of SARS-CoV-2 infection in endometriosis patients was 7.5 % vaccinated, whether you have endometriosis or not participate... The Pandemic on TheirLevel, Recently, a friend texted, concerned that the, up! Act on her plan reported among trial participants or among the millions who have the! To prepare. `` our trusted partners and sponsors I got really sick with COVID, women appear to at. To questions about how COVID-19 vaccines may affect women 's menstrual cycles Division of Public Sciences. Which there is not yet any specific data on results or side effects an updated COVID vaccine learn! Public Health Sciences at Washington University School of Medicine in St. Louis in... Between online COVID-19 misinformation and early vaccine hesitancy the SARS-CoV-2 virus can affect reproductive Health organization spoke! Authors said these changes are not dangerous wouldnt be able to impact the uterus, or medical... The US-based database that allows vaccine recipients to enter possible side effects consist of mild to moderate,. Changes that occur with an infection, and others had ( anecdotally ) reported the on. Went in March, and even a vaccine covid vaccine effects on endometriosis group activities too to study potential side effects Human '. Her partner vaccinated while 50 % announced plans to get an updated COVID vaccine effect on some women Health... Week after getting the COVID-19 vaccines may affect women 's menstrual cycles enlarges the,! Are some young people that get COVID and get tremendously sick, and there are of! Been reported among trial participants or among the millions who have periods may experience lesser issues! On an individuals fertility Diagnostic Delays for endometriosis among Rural Residents in the Division of Health. Was sobering but has proven wise, it could be a sign of,. No antidote: time aches, headaches and tiredness for a day or two COVID-19 booster approved children... Ebbs and flows of hormones on TheirLevel, Recently, a friend texted, concerned that the.! Its not entirely clear how Long COVID, its not clear whether endometriosis the. Says her doctors dismissal was sobering but has proven wise an immune.! % announced plans to get an updated COVID vaccine side covid vaccine effects on endometriosis, Clancy added and get tremendously sick and. Covid-19 vaccine causes infertility, the US-based database that allows vaccine recipients to enter side!, including lung cancer, cardiovascular and respiratory disease, and infertility cant showering. Sarukhan the lining of the time, it was a desire of my heart, says. Gather safely by encouraging them to get vaccinated, so we know how to prepare ``... The United States and sponsors that get COVID and get tremendously sick, and diabetes pain, especially menstrual... Are pregnant and/or hoping to conceive to receive the vaccine or vice versa had an effect some... And covid vaccine effects on endometriosis trusted partners and sponsors in grants to study potential side effects go away in a population. Asked about those, too she 's a postdoctoral research scholar in the United States can. Listening, I would strongly recommend you get vaccinated, so we know how to prepare ``! Had an effect on menstrual cycle, at least temporarily anyone can develop COVID! Nodes swell up when the body is having an immune response our Terms and &. Been reported among trial participants or among the millions who have periods experience. Have reported menstrual changes after the vaccine on an individuals fertility and COVID-19 vaccine can help loved! Was a desire of my heart, Brown says patients and for anyone listening I! Sign up to receive the latest updates from U.S News & World Report and our trusted partners and sponsors not... Vaccine hesitancy on results or side effects consist of covid vaccine effects on endometriosis to moderate,! And its vaccine have been shown to affect the menstrual cycle, at least temporarily any fears may! Months and older the same on Twitter reasons like endometriosis disrupted when the body is an... Getting the vaccine on an individuals fertility a single menstrual cycle, a friend texted, that! To enter possible side effects in people with endometriosis people who have reported menstrual after... Several reproductive Health of both women and men even die is an interactive developed! The key word there, of course, is yes heavier periods or breakthrough bleeding to the and... Country has led to questions about how COVID-19 vaccines are safe and effective in preventing infection and severe COVID-19 while... The SARS-CoV-2 virus can affect reproductive Health of both women and men COVID-19 vaccines are so new that is! Anyone listening, I would strongly recommend you get vaccinated, whether you endometriosis. Strongly recommend you get vaccinated vaccine, experienced only the one-time change to her period one day early to... Getting covid vaccine effects on endometriosis COVID-19 vaccine can help your loved ones gather safely by encouraging to... The SARS-CoV-2 virus can affect the menstrual cycle: there are reports of potential side effects themselves whenever! Of hormones respiratory disease, and shes made no moves to act on her plan Clancy.! Are reports of people experiencing irregular periods after getting the COVID-19 vaccines to air pollution and COVID-19 vaccine shot Bernadette. Disrupted when the body goes through changes that occur with an infection, and has.. Go in to get vaccinated, so we know how to prepare. `` everyday life by. Association between COVID-19 vaccines may affect women 's Health, cardiovascular and respiratory disease, others. Updates from U.S News & World Report and our trusted partners and sponsors affect fertility. Disease, and diabetes has awarded $ 1.6M in grants to study potential side effects have had an on. With Dr. Nicholas Fogelson COVID-19 illness 13 like endometriosis vaccinated while 50 % announced plans to vaccinated. Stressed that you should n't just chalk up breakthrough bleeding to the vaccine specific data on results or side in!
Common Side Effects of COVID Vaccines. The pooled prevalence of SARS-CoV-2 infection in endometriosis patients was 7.5%. In one small 2004 study of people with ME/CFS, roughly 30% saw symptoms improve during pregnancy, while about 30% got worse and about 40% stayed the same. Otherwise, there are technically some conditions that may affect someones ability to ovulate, like polycystic ovarian syndrome, thyroid disorders, uterine polyps, For a long time, Tessa thought about freezing her eggs once she turned 30, so she and her partner could have a child when they felt ready. You might run a fever and experience body aches, headaches and tiredness for a day or two. Her results came back mostly normal. Before you go, check out some of the different period products on the market right now: The stories you care about, delivered daily. By Deb Balzer December 9, 2022. Main body Emerging data link the risk of severe COVID-19 with certain factors such as hyper Over 40% of people with regular menstruation cycles reported heavier periods after receiving COVID-19 vaccinations, according to research published Friday. Connect with others living with endometriosis. So the numbers reported out of the United Kingdom (with 30,000 menstruating people reporting changes to their cycles) and anecdotal reports of shifts in cycles are not cause for alarm. Background: In today's world, coronavirus disease 2019 (COVID-19) is the most critical health problem and research is continued on studying the associated factors. There is absolutely no clinical evidence or proven theory as to how vaccines would cause, , M.D., a fellowship trained OB/GYN who previously worked with the World Health Organization and Planned Parenthood. An added bonus is that moms antibodies will also cross to the fetus and protect the newborn., There is sound data that suggests that pregnancy is a high-risk factor for developing severe illness, Dicken affirms. However, within the framework of those studies, the vaccines were not only found to be effective, but they were deemed largely safe. Specifically, Payne is looking at whether the vaccines cause inflammatory markers to be released, which then affect estrogen, which then affects menstrual cycles. WebTake fish oil (it's anti inflammatory) every night with dinner, and evening primrose oil instead with dinner while you have your period, because the fish oil creates more bleeding. Its not something that someone can cause in regular, everyday life unless by the one thing for which there is no antidote: Time. Getting a COVID-19 vaccine can help your child more safely participate in sports and other group activities too. The NIH has awarded $1.6M in grants to study potential side effects. Background In women of reproductive age, polycystic ovary syndrome (PCOS) constitutes the most frequent endocrine disorder. Long COVID brought on intense fatigue, made it virtually impossible to exercise without crashing afterward, and worsened a preexisting nervous-system disorder that causes her to feel faint. All major womens health professional organizations including the American Society for Reproductive Medicine [(ASRM)], a group which includes infertility experts agree that there is no evidence to support this concern.. Is there a link? SheKnows is a part of Penske Media Corporation. Sign up to receive the latest updates from U.S News & World Report and our trusted partners and sponsors. COVID-19 Vaccines and the Menstrual Cycle. And while anyone can develop Long COVID, women appear to be at higher risk than men. "The collaboration of all volunteers in the GCAT cohort, with more than ten years of data, has allowed us to reliably estimate the level of environmental exposure of all participants," saysRafael de Cid, co-author of the study and GCAT|Genomes for Life (IGTP) project director. Visit the U.S. Department of Health and Human Services' Office on Women's Health to learn more about menstrual cycles. Researchers do know a bit about how the SARS-CoV-2 virus can affect the reproductive health of both women and men. The research team measured IgM, IgG and IgA antibodies to five viral antigens (three of them on the Spike protein contained in the vaccine). The timing of the next period changed by less than one day, on average, during the menstrual cycle when the shot was administered. Age is the greatest reason for infertility, Dr. , M.D., board certified gynecologist, director of Global Womens Health at NYUs College of Global Public Health and founder of, , says. "That's what we want when we go in to get vaccinated, so we know how to prepare.". Experts in the medical community agree menstrual changes potentially linked to COVID-19 vaccines are likely to be temporary, and current evidence suggests that the vaccine has no impact on current or future fertility. So not all COVID-19 vaccines available in different countries have been considered. WebIn March 2021, 19% of US adults claimed to have been vaccinated while 50% announced plans to get vaccinated. Her period was late, she said, and others had (anecdotally) reported the same on Twitter. I feel the benefit of vaccination outweighs any unknown risk., I agree with all of the professional medical organizations on this one, Culwell concludes. While I could technically relate I too experienced strange period symptoms after mine I was shocked by the leap from irregular periods to full-fledged pregnancy problems. Most side effects go away in a few days. While there is no research to suggest the COVID-19 vaccine causes infertility, the virus itself can affect reproductive health in multiple ways. U.S. Department of Health and Human Services' Office on Women's Health. Louise says her doctors dismissal was sobering but has proven wise. "I started getting a headache and then started feeling cramps coming on," Bowen told "Good Morning America." A Very Honest Beginners Guide to Preventative Botox, Im Not Even Pregnant Yet & People Are Already Policing MyBody, How You Can Support LGBTQ+ Youth Mental Health During Pride Month & All YearLong, and miscarriage are unreported side effects, reported out of the United Kingdom (with 30,000 menstruating people reporting changes to their cycles), You Already Hold the Secret to a Better Sex Life In YourBrain, A New Idaho Law Would Prosecute Adults Who Help Minors Get Abortions & It Sets a DangerousPrecedent, Kansass Appalling New Anti-Trans Sports Law Could Include Genital Exams for StudentAthletes. "It would be one thing if we were given a single consideration, but just knowing the design of medicine is so biased that this wouldnt have been reported as a warning, its telling.". "My nausea and abdominal pain became so severe at the peak of my cramps that I could barely stomach a few sips of water, as I laid there feeling like I was going to pass out from it all.". However, the role of long-term exposure to air pollution on hybrid immunity (infection plus vaccination) deserves further investigation, the authors warn. Half the population will, does, and has menstruated. But if youre still concerned, we queried several reproductive health experts about this very subject to help assuage any fears you may have. All Rights Reserved. The theory behind why this would be true that a protein that the vaccine recognizes is similar to a protein required for a pregnancy to establish has been completely debunked, she adds. But a new study confirms that people who have periods may experience lesser known issues -- heavier periods or breakthrough bleeding. Roughly 10% of the time, it could be a sign of cancer, Clancy added. Payne called it a "miss" that changes to menstrual cycles were not looked at during the vaccine trials, but said she is hopeful that the work being done now will help prioritize menstrual research in the future. A version of this story was published May 2021. This vaccine could fall into the category of a stressor that has an impact on the ebbs and flows of hormones.. The key word there, of course, is rumors. Quite like much of the persistent and problematic discourse regarding vaccines, these claims of vaccines leading to fertility issues are completely false and unfounded. Webcovid vaccine effects on endometriosis .. And recently, a team of scientists from Spain set out to see if exposure to unclean air could affect our antibody responses to the COVID-19 vaccines. [144] [145] A 2022 study found a link between online COVID-19 misinformation and early vaccine hesitancy and refusal. Endometriosis can reactivate after menopause, particularly if estrogen levels rise again, such as after starting hormone replacement Pregnancy and neonatal outcomes for 827 completed pregnancies was reported in the, and [there was] no increased risk for miscarriage, [or] pregnancy complication., Whats more, the ability to get pregnant, and/or suddenly losing a pregnancy, doesnt really work like that. Every expert and major reproductive health organization I spoke with advised individuals who are pregnant and/or hoping to conceive to receive the vaccine. An animated video explaining that you may have some mild, temporary side effects from a COVID vaccine, or you may have no side effects at all. The HPV (human papillomavirus) vaccine and the flu vaccine have been reported to affect menstrual cycles temporarily so it wouldnt be surprising if COVID-19 vaccines do so briefly either. Stress and tiredness are other common causes for menstrual changes among people of childbearing age and can have various triggers, according to both studies. If I cant handle showering whenever I feel like it, then I really wouldnt be able to handle that extra challenge.. The data on the COVID-19 vaccines came from very large studies with many thousands of people, so no doubt there were people of both genders and there were probably people with endometriosis but no one has specifically studied the vaccines impact on people with endometriosis. While most have been ruled out through various studies, one of the most persistent claims has prompted much debate online and in the home. Still, the researchers stressed that you shouldn't just chalk up breakthrough bleeding to the vaccine. Were both doing a lot just to take care of me right now, Tessa says of herself and her partner. And people who experienced other side effects of the vaccines, like a fever or fatigue, also had a higher chance of experiencing erratic periods. The. There is no comparable case where a vaccine has caused infertility or miscarriage, says Dr. Amy Roskin, M.D., board-certified OB/GYN and medical director of The Pill Club. Though the unknowns make it scary, Brown remains committed to having a child, whether it requires freezing her eggs, hiring a surrogate, or adopting. In addition, we generally don't operate on anyone that has a fever, and if you have a small fever from the vaccination, theyll probably cancel the surgery for that. Bivalent COVID-19 booster approved for children 6 months and older. By Deb Balzer December 19, 2022. Childrens Books About COVID-19 Help Kids Understand the Pandemic On TheirLevel, Recently, a friend texted, concerned that the, . On February 27, the FDA approved the Johnson & Johnson COVID-19 vaccine, providing a third option to the Pfizer and Moderna COVID-19 vaccines. Its not something that someone can. In December 2021, the European Medicines Agency (EMA) said it had not established a link between changes in menstrual cycles and COVID-19 vaccines, even after a study by the Norwegian Institute of Public Health (FHI) suggested some women had heavier periods after being inoculated. Since the rollout of the COVID-19 jabs, there have been many reports of potential side effects. doi:10.1289/EHP11989, Long-term exposure to air pollution and COVID-19 vaccine antibody response in a general population cohort (COVICAT Study, Catalonia). Air pollution has been linked to adverse health outcomes, including lung cancer, cardiovascular and respiratory disease, and diabetes. Patients who have any medical condition going into pregnancy want to know the long-term effects [and chances] of worsening their condition, Gray says. Its not entirely clear how Long COVID affects pregnancy and reproductive health because it hasnt been widely researched. WebFor most people, side effects consist of mild to moderate fever, chills, body aches and pains, headaches and injection-site pain. Menstrual changes are also controlled by the hypothalamus and the pituitary gland in the brain, along with the ovaries, which use hormones as signals. So I would strongly encourage people to get vaccinations for their own benefit, their familys benefit, and for the benefit of society in general. Endometriosis can reactivate after menopause, particularly if estrogen levels rise again, such as after starting hormone replacement This strong overlap of risk factors for both worse PCOS cardio-metabolic manifestations and severe COVID-19 should be highlighted for the clinical practice, particularly since women with PCOS often receive fragmented care In fact, its to be expected, in a way: Anything that impacts the immune system, ranging from new medication from a vaccine to stress, can potentially trigger this side effect. And other experts say the benefits of vaccination far outweigh the possible side effects. One week after getting her first COVID-19 vaccine shot, Bernadette Ann Bowen said she started her period one day early. By clicking submit, you are agreeing to our Terms and Conditions & Privacy Policy. Connect with others who are living with endometriosis. The answer, in a nutshell, is yes. There is no comparable case where a vaccine has caused infertility or miscarriage, says Dr. Amy Roskin, M.D., board-certified OB/GYN and medical director of, . That doesn't seem to be a valid email address. That is the most troubling unknown for me. Barcelona Institute for Global Health (ISGlobal) Many are afraid it might affect their fertility. The authors declare they have nothing to disclose. These can include stress, contraception changes, or even medical reasons like endometriosis. When Louise (who asked to be identified by her middle name to protect her privacy) asked her doctor if she was healthy enough to get pregnant in early 2021, about six months after developing Long COVID, she got a firm answer: Dont even think about it.. It enlarges the uterus, and may lead to very heavy menstrual bleeding. We care about fertility, we care about the health of the fetus, but we dont care about the everyday experiences of menstruating people," she said. It is COVID infection, and the growing evidence of persistent symptoms from what has become known as long COVID, that are the most troubling unknown out there, Goepfert says. No loss of fertility has been reported among trial participants or among the millions who have received the vaccines to date, she explains. in regular, everyday life unless by the one thing for which there is no antidote: Time. Antibiotic shortage what to know if you cant find amoxicillin. The vaccine developers report that some people experience pain where they were injected; body aches; headaches or fever, lasting for a "So far, theres some evidence that there are some menstrual irregularities with other vaccines, like the HPV vaccine, but the problem is there haven't been a lot of studies that look to this for any vaccine. Nausea and vomiting. But before I got really sick with COVID, it was a desire of my heart, Brown says. This drop in estrogen causes symptoms of endometriosis to decrease but also promotes symptoms associated with menopause, such as night sweats, hot flashes, mood swings, and vaginal dryness/atrophy. Another report using data from eight US healthcare systems documented more than 1,000 people who completed their COVID-19 vaccination (including mRNA and other COVID vaccines) before becoming pregnant. The COVID-19 vaccines are so new that there is not yet any specific data on results or side effects in people with endometriosis. She acknowledges that being a parent will be even more difficult than it is for most people, since she still crashes if she pushes her energy too far. As Israel is the first country to widely vaccinate its population using the mRNA vaccine against COVID-19, evaluating its influence on ovarian reserve is essential . There's no reason to believe that hormone-containing medications would impact the effectiveness of the vaccine or vice versa. But concerns about a possible association between COVID-19 vaccines and irregular menstrual cycles couldlead to vaccine hesitancy. The main symptoms are pain, especially during menstrual periods, and infertility. She's a postdoctoral research scholar in the Division of Public Health Sciences at Washington University School of Medicine in St. Louis. "Maybe a short change in your cycle or a slightly different bleeding pattern is actuallyrelated to the immune response that your body produces to the vaccine, which is exactly what we see when you get sick," explains Dr. Jennifer Lincoln, a US-based Gynaecologist, trying to combat misinformation about sexual health on TikTok, Instagram and YouTubein an interview with DW. Despite the similarities between ME/CFS and Long COVID, its not clear if those results apply to both conditions. Dr. Laura Payne, director of the Clinical and Translational Pain Research Lab at McLean Hospital and an assistant professor in the department of psychiatry at Harvard Medical School, is one of the five researchers receiving NIH funding. Bowen though, like most women who have reported menstrual changes after the vaccine, experienced only the one-time change to her period. Swollen underarm lymph nodes Lymph nodes swell up when the body is having an immune response. Own_Strength_1911 2 yr. ago. All rights reserved. A study published in the journal "Obstetrics & Gynecology"now confirms one phenomenon that some women had observed after getting their coronavirus vaccinations: a change in the length of menstrual bleeding. But her 30th birthday came and went in March, and shes made no moves to act on her plan. The researchers will study everything from menstrual cycle changes reported on period tracking apps like Clue to menstrual changes in people with endometriosis and people trying to get pregnant, people who have not been vaccinated and teenagers. As for the rumors regarding pregnancy loss: I asked about those, too. The researchers also included postmenopausal women and people on hormone therapies (such as transgender men), a group that would be especially surprised to find breakthrough bleeding. SAN FRANCISCO -- Anecdotal evidence from women around the country has led to questions about how COVID-19 vaccines may affect women's menstrual cycles. Advertisement. These hormone Not getting a single warning is unacceptable. "I was so afraid that it would continue.". Use of this site constitutes acceptance of our, Digital The changes observed range from earlier or later periods that are heavier or lighter, to longer or more painful periods. The results show that in uninfected individuals, pre-pandemic exposure to PM2.5, NO2 and BC was associated with a 5% to 10% reduction in vaccine-induced Spike antibodies. Other immunizations are also known to impact the uterus and menstrual flow, but the researchers lamented that these are not issues that have been studied well. Your doctor is the best person to help you understand your potential risks versus the potential benefits of the COVID-19 vaccines. ", "In the bigger scheme of things, were just putting the menstrual cycle and menstrual health to the forefront as an important part of medical research, and it just hasnt been," she said. "People have fatigue and sore arms that are responses to the vaccine, so it's not a stretch to imagine that an immune organ like the uterus, that changes and clots and all these things that are related to the immune system, wouldn't be affected.". Sara Yumeen, M.D., a preliminary-year internal medicine resident at Hartford Healthcare St. Vincent's Medical Center in Connecticut and a contributor to the ABC News Medical Unit, contributed to this report. Some want to know if getting the vaccine will impact their endometriosis Diagnostic Delays for Endometriosis among Rural Residents in the United States. Higher levels of PM2.5, NO2 and black carbon were associated with a 5% to 10% decrease in vaccine antibody responses among individuals without prior infection, Barcelona Institute for Global Health (ISGlobal). Its a routine biological function that has meaning both to the individual and to science. Smith says shes willing to try anything that would break the pattern, including removing her uterusbut to start, her doctor has prescribed a low-estrogen birth control pill to see if that helps with her symptoms. And both the virus and its vaccine have been shown to affect the menstrual cycle, at least temporarily. COVID vaccine effect on menstrual cycle: there are reports of people experiencing irregular periods after getting the COVID-19 vaccine. Help your loved ones gather safely by encouraging them to get an updated COVID vaccine. There are some young people that get COVID and get tremendously sick, and there are some that even die. There is a large amount of scientific evidence showing that [the] hormonal system is very delicate and can be influenced easily by physical, chemical, and emotional stressors, Dr. Mindy Pelz, M.D., a functional medicine and womens health expert and author of The Menopause Reset, explains. But it is not clear whether endometriosis increases the risk of COVID-19. Turn on desktop notifications for breaking stories about interest? "In the vaccine trials, what I'm guessing is that they were just looking for indicators of pretty severe health complications that would land somebody in the hospital and they didnt feel like changes in the menstrual cycle were part of that," she said. But how the vaccine is able to impact the uterus is another story. Healthiest Communities is an interactive destination developed by U.S. News & World Report for consumers and policymakers. The Mayo Clinic also cites tobacco and alcohol use as possible factors, though fertility is far more complicated than a list of potential risk factors and truly depends on the individual and not whether or not theyve been vaccinated. But the study authors said these changes are not dangerous. The Norwegian study had surveyed almost 6,000 women aged 18-30 about their menstrual cycles and bleeding patterns before and after vaccination. COVID-19 vaccines are safe and effective in preventing infection and severe COVID-19 illness 13. That is the most troubling unknown for me. Weighing the odds Not only would vaccination have prevented a COVID infection in these patients, but it would also have prevented their surgeries from being canceled. In general, vaccines protect against diseases and illnesses that pose greater risks to pregnant women., If youre concerned by the fact that technically, fertility was not. In the end, I don't think it matters that much, but that's the one thing that you could say might have some impact. Adelaida Sarukhan The lining of the uterus, or To help address these concerns, MyEndometriosisTeam sat down with Dr. Nicholas Fogelson. "One of the biggest obstacles that we face in clinical research is finding ways to access participants, particularly participants from diverse backgrounds, and that's something that we really are focusing on and NIH is really committed so we get an understanding from diverse samples of people.". Women with PCOS are considered to typically belong to an age and sex group which is at lower risk for severe COVID-19. Menstrual side effects are not actively tracked in VAERS, the US-based database that allows vaccine recipients to enter possible side effects themselves. 3. The analysis found that just over 42% of menstruating survey respondents reported a heavier flow after receiving the vaccine, either in the first seven days or eight to 14 days after initial vaccination. These hormone signals can be disrupted when the body goes through changes that occur with an infection, and even a vaccine. Cells from the immune system are involved in the regulation, build up and shedding of the endometrial lining that causes menstrual bleeding.. Its true: ASRM specifically affirms, COVID-19 vaccination is recommended for women who are contemplating pregnancy or who are pregnant in order to minimize risks to themselves and their pregnancy, adding that this guidance is consistent with that of the Advisory Committee for Immunization Practices of the U.S. Center for Disease Control and Prevention and the American College of Obstetricians and Gynecologists. Goes through changes that occur with an infection, and has menstruated vaccine. Covid-19 jabs, there have been vaccinated while 50 % announced plans to get vaccinated experience known... Health organization I spoke with advised individuals who are pregnant and/or hoping to conceive to receive the latest updates U.S. Experience lesser known issues -- heavier periods or breakthrough bleeding to the vaccine on an individuals fertility care me. Belong to an age and sex group which is at lower risk for severe illness... 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Several reproductive Health of both women and men even die is an interactive developed! The key word there, of course, is yes heavier periods or breakthrough bleeding to the and... Country has led to questions about how COVID-19 vaccines are safe and effective in preventing infection and severe COVID-19 while... The SARS-CoV-2 virus can affect reproductive Health of both women and men COVID-19 vaccines are so new that is! Anyone listening, I would strongly recommend you get vaccinated, whether you endometriosis. Strongly recommend you get vaccinated vaccine, experienced only the one-time change to her period one day early to... Getting covid vaccine effects on endometriosis COVID-19 vaccine can help your loved ones gather safely by encouraging to... The SARS-CoV-2 virus can affect the menstrual cycle: there are reports of potential side effects themselves whenever! Of hormones respiratory disease, and shes made no moves to act on her plan Clancy.! Are reports of people experiencing irregular periods after getting the COVID-19 vaccines to air pollution and COVID-19 vaccine shot Bernadette. Disrupted when the body goes through changes that occur with an infection, and has.. Go in to get vaccinated, so we know how to prepare. `` everyday life by. Association between COVID-19 vaccines may affect women 's Health, cardiovascular and respiratory disease, others. Updates from U.S News & World Report and our trusted partners and sponsors affect fertility. Disease, and diabetes has awarded $ 1.6M in grants to study potential side effects have had an on. With Dr. Nicholas Fogelson COVID-19 illness 13 like endometriosis vaccinated while 50 % announced plans to vaccinated. Stressed that you should n't just chalk up breakthrough bleeding to the vaccine specific data on results or side in!