Many antidepressants have been shown to increase BDNF levels in astrocytes. Results demonstrate that bFGF is necessary for the proliferation of neural precursor cells and that the glycogen synthase kinase-3β (GSK-3β) and β-catenin pathway plays a role in it.... Diffusion tensor imaging (DTI) is considered to be able to non-invasively quantify white matter integrity. Takeshi Inoue's 212 research works with 4,211 citations and 7,520 reads, including: Associations between the depressive symptoms, subjective cognitive function, and … Although sleep affects mental health and presenteeism, the associations between sleep disturbance, job stressors, stress responses, and presenteeism have remained unclear. Method... Background: Stress during postnatal development is associated with an increased risk for depression, anxiety disorders, and substance abuse later in life, almost as if mental illness is able to be programed by early life stressors. In this study, we investigated how the complex effects of subjective social status, childhood abuse, and affective temperament influence depressive symptoms in adulthood. This study was undertaken to examine the long-term effectiveness and safety of switching to sertraline from other selective serotonin reuptake inhibitors (SSRIs) in the treatment of non-remitted or treatment-intolerant major depressive disorder. It has been shown that, although depression decreased the level of dopamine in the PFC, antidepressant drugs such as SSRIs, TCAs, and SNRIs increased it, which suggested the essential role of PFC dopamine level in the depression. Our previous study reported that subchronic lithium treatment enhanced the anxiolytic-like effect of systemic mirtazapine. Using in vitro culture of adult rat DG-d... We reviewed recent advances in biological studies of anxiety disorders. I... Background A comprehensive assessment of the effects of life habits on sleep in high-school students was conducted. Differences between bipolar and unipolar depression on Rorschach testing, Maternal Separation Attenuates Neural Differentiation of Adult Dentate Gyrus-Derived Neural Precursors Through Increasing DNA Methylation of RAR alpha Promoter, GDNF facilitates differentiation of the adult dentate gyrus-derived neural precursor cells into astrocytes via STAT3, Development and validation of a screening questionnaire for present or past (hypo)manic episodes based on DSM-IV-TR criteria, The valproate serum level in maintenance therapy for bipolar disorder in Japan, Temperament and character profiles of Japanese university student suicide completers, Effects of combined treatment with clorgyline and selegiline on extracellular noradrenaline and serotonin levels, ROCK2 regulates bFGF-induced proliferation of SH-SY5Y cells through GSK3 beta/beta-catenin pathway, Impaired integrity of the brain parenchyma in non-geriatric patients with major depressive disorder revealed by diffusion tensor imaging, Effect of triiodothyronine (T3) augmentation of acute milnacipran administration on monoamine levels: An in vivo microdialysis study in rats, Utility and limitations of PHQ-9 in a clinic specializing in psychiatric care, 5-HT depletion, but not 5-HT1A antagonist, prevents the anxiolytic-like effect of citalopram in rat contextual conditioned fear stress model, Involvement of CaMKIV in neurogenic effect with chronic fluoxetine treatment, The effects of the co-administration of the α1-adrenoreceptor antagonist prazosin on the anxiolytic effect of citalopram in conditioned fear stress in the rat, Sertraline treatment of patients with major depressive disorder who failed initial treatment with paroxetine or fluvoxamine, Mood stabilizers commonly restore staurosporine-induced increase of p53 expression and following decrease of Bcl-2 expression in SH-SY5Y cells, Social Anxiety/Taijin-Kyofu Scale (SATS): Development and Psychometric Evaluation of a New Instrument, Beneficial effects of physical activity on depressive and OCD-like behaviors in the male offspring of morphine-abstinent rats, Prevention of depression in first-year university students with high harm avoidance: Evaluation of the effects of group cognitive behavioral therapy at 1-year follow-up, The Astrocytic cAMP Pathway in Health and Disease, An explanatory model of factors enabling sustainability of let’s talk in an adult mental health service: a participatory case study, Association between coffee, tobacco, and alcohol daily consumption and sleep/wake cycle: an actigraphy study in euthymic patients with bipolar disorders. Mood stabilizers including lithium (Li) and valproate (VPA) increase it. ... 33 They further suggested that improving sleep hygiene and lifestyle could improve sleep disturbance. This study was set out to investigate the association between BZPs and rehospitalization of patients... Introduction: [10][11]. Metho... Calcium-calmodulin dependent protein kinase IV (CaMKIV) is a protein kinase that has been suggested to participate in fluoxetine (FLX)-induced phosphorylation of cyclic AMP-response element binding protein (CREB). We collected data from... Background: Occupational mental health, work environment, sleep health, presenteeism, and loss of work productivity caused by health problems are all public health concerns. However, a valid shortened version is desired for large-scale investigations to enhance the compliance of respondents. [1], Inoue died on April 5, 1992 at the age of 63. Thus, we evaluated correlations among childhood parenting, affective temperaments, depressive sym... Background: We recently demonstrated in the structural equation modeling that four of five affective temperaments, as measured by the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego auto-questionnaire version (TEMPS-A), are strong mediators between childhood abuse and depressive symptoms in the nonclinical general adult population. The most important achievement was the discovery of the neural circuits of fear in the 1990s by using an animal model in which conditioned fear was induced. At this qualification, on March 7, he debuted against South Korea. Recent studies suggest that such "programmed" effects can be caused by epigenetic regulation.
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