I have an 8-year-old Shih Tzu who had more or less uncontrollable itching, mostly she would bite at her paws but then the itching became worst all over. She has kept me awake for the last few nights constantly getting up and wandering because she feels so sick. BTW, we cleaned up her diet and such, but some of the natural remedies suggested above are almost impossible to administer to my dog. I took my 58# This medicine stopped the itch and it had wonderful results UNTIL recently she had 2 seizures!!!! I am a Healthcare professional and I somehow missed important information. I dont think dogs are suddenly getting allergies. Does that sound about right? (Medicine service at Purdue Such as, what is the correct hydroxyzine dosage for dogs? When I do find him upstairs he is comatose and has vomited all around the house and done a poo in the family room. An OTC alternative might be Benadryl for your dog. None of these worked brilliantly but they did have an effect on reducing some of his symptoms. She has been on 3 primary seizure drugs used in humans for almost a year now. Fourth Quarter 2014 Revenue of $1.3 Billion Increased 5% Compared to Fourth Quarter 2013 While it is not approved by the US-FDA for use in pets, veterinarians generally prescribe (Rx only) it as an extra-label drug. We adopted this puppy from the Animal Defense League 2/16/2016. Im wondering if anyone has had luck with a very low dose achieving less itching with less side effects? we didnt have fleas. After the allergy tests I gave him Natural Balance Sweet Potato and Fish, which he doesnt eat much so I add other things to it. No, I dont think I will give it to him again. Redness . (Answered 2023), Can Dogs Eat Ruffles Chips? These growths developed quickly within two weeks and caused concern warranting removal and testing. Having treated hundreds of dogs for allergies, it is MORE than welcoming to have a drug that works to STOP the itching without all the side effects of predisone. Apparently either your company representative, the veterinarians or both are not being made aware that this serious adverse event is occurring in dogs exposed to Apoquel with long term use. http://www.dogsnaturallymagazine.com/wouldnt-give-dog-new-allergy-drug/. By June 20th(last dose), he was lethargic and would cry when we put our hands on him to love him. I cannot believe his Dr. gave a medicine that might cause gastro-intestinal problems and suppress the immune system to a puppy that has a weaken immune system from mange and had recent stool and vomiting issues. This is how hydroxyzine is used on humans. He takes 16 mg. daily and the scratching has almost stopped. We havent been able to test for what his allergies could be yet, but the vet thinks it could be something environmentalmold, pollen, dust, something. He has woken up several times in the middle of the night to go outside and have diarrhea multiple times, then he strains and lays down on his stomach. He was gone 6 days later. It makes him miserable! Your article leads people like Lynn with the yorkie to jump to blaming Apoquel for her dogs health issues with nothing to substantiate her claim. Apoquel can be used along with: antibiotics antifungals anti-arthritis drugs Your vet may prescribe it to relieve the symptoms of an allergic reaction. She said he would sleep it off. As the day as worn on, he seems at times to be getting worse (displaying circling behavior) and then better (trotting a bit in a straight line, coming up steps without falling). I decided to look up the side effects of Apoquel, as that was the only thing that was new and I wondered if GI upset and diarrhea could become an issue while on it. Metacam with known renal and liver side effects. He has symptoms of Cushings from longterm use of the Pred and he has a heart murmur. University) This is what I believe happened to my Baby Girl Knowing the medication was the only new thing in his routine, we stopped it. Its been 2yrs of no Atopica. I pray that there was no long term damage done. And only started happening when she went back on the drug. Thanks for your advise earlier about the beta 3. I am seriously thinking this drug is to blame. We actually had to feed her out of our hand or put the food on he floor because I think she was afraid of Apoquel in her dog bowl ( yes I believe pets are smart line this). But now, she has just had a huge tumor removed from her leg and it is considered to me a Mast Cell Tumor, most likely Level 3 (we are waiting for the final lab report), but this now is very bad. Stopped giving it to her and in 48 hours, she is spunky again. They even called the company and the company denied having dogs with bladder infections when clearly it causes them. The vets are making a fortune off this drug and the injections that is why they are pushing them. The vet recommended apoquel. Please let me know what I can do to help get this drug off the market. Stellas diet is I bunch of spinach, 4 carrots, I head of broccoli and 4 sticks of celery, raw, blitz it up in a food processor, add 5 boiled eggs, shells included. Dogs are able to take hydroxyzine. I was assured this drug was safe. Her stools are turning around and while still soft, are not the plop plop plop anymore. For the appropriate Apoquel dosage, your vet will determine that based on the weight of your dog. This year is especially bad. Its all about the money! My 7 year old male GSD has been on apoquel for 2+ years now for horrible scratching due to atopic dermatitis. We also have trazodone from her past vet (we switched 6 months ago) for her bad car/boarding anxiety. And I know she picked the profession she did because of a passion for animals. These medications may cause some risk when taken together. And the drug company should be ashamed of there self. I wouldnt take our dogs almost considered human to a vet i didnt trust. In studies, dogs were treated with APOQUEL for more than 2 years. Its crazy how fast that can happen. When I looked them up I immediately stopped the drug but it was too late. The routine veterinarian drug did not bring it down. But, sometimes this is the desired outcome. How to Report Apoquel Side Effects in Dogs Apoquel side effects in dogs can be reported directly to the manufacturing company. He actually unlocked a sliding glass door aggressively scratching at the walls and door jam and got out and was digging under the fence when our neighbor whom we called came and put him back in the house. Metronidazole (also known by the brand names Flagyl, Metizol, Protostat, Metrogel) is a strong antibiotic primarily used as an antidiarrheal to treat inflammation of the large intestine. BTW, these meds did not come with the normal info sheet, just directions on the bottle. Keep in mind she has been on the Apoquel since the spring of 2014 when it came out. The itching has come back full blown .. bumps swollen paws ect. I think a class action suit against the makers of apparel is called for. I am trying the drug today onwards for my baby and Im hoping for good results and hopefully no side effects will let you know. When we told the vet we wanted to discontinue this because of the side effects she acted like she has never heard of anyone having hear issues before. My 12 year old German Shepard mix was prescribed Apoquel for seasonal allergies after Zyrtec wasnt effective. In fact, the other drugs used for this condition carry similarly disturbing side effects. Benadryl wasnt working so Dr. prescribed Apoquel 6/9/2016. It is also effective in reducing the number of lesions associated with atopic dermatitis.. Try the new diet for 4 weeks. Prednisone is a steroid and Apoquel is an immune modulator drug that specifically targets the receptors on your pets skin that cause itching. I agree. I wouldnt recommend it after our issues with it and reading others comments. Apoquel Side Effects. Or decide that treating your dogs itchiness another way will yield the best results. If you love your dogs please dont give them Apoquel. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery. She never did the digging thing previously. That was a year ago. These include the severity of the symptoms, the size of your dog, and any existing treatments or illnesses your dog has. Hes been to Cornell, and we have tried just about everything. dog? Ever since this move, my dog is itching & scratching often. Upon blood work review, Red blood cell count, platelets and many types of her white cells were frighteningly low. The answer is: it depends on the weight of your dog. Dogs with the MDR1 genetic mutation can become very ill or die if given certain medications. Its incredible how this drug is not off the market!! Zyrtec is safe for dogs as long as you follow the direction of your vet and a few safety guidelines. Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. We were dealing with our older Chocolate Lab on Nov 7 who we had to put down, so I forgot to keep an eye on my Ginny. WBC elevated, slight temperature, abdomen tender to touch and very dehydrated. He itched and scratched since we got him. please do not give your pets this drug. In his 10 years he has never defecated in the house. What are the side effects of hydroxyzine in dogs? I appreciate the work that Dr. Jones is doing. He stares blankly without focusing. I do not recommend this medication. My 4 year old Yorkie was put on apoquel. He has a low platelet count. Took him to the vet again for a full blood workup which the vet tells me was fine. She was given a shot of something at the vet to help with itching. I cant wait for winter so I can see if I can take him off Apoquel and see if his weight goes down. Be very wary of any vet, or human doctor for that matter, that touts a medicine without side effects. Her itching was better but not eliminated. I was never told this drug is an immunosuppressent. Like everyone else it helped make her more comfortable at first then increased eating and lethargy. This morning at 5am, I took Peatie out for his early morning peepee and in a rain storm, he dropped on the sidewalk and seized upin a puddle of water on the cold sidewalk, my best friend had completely lost control of all bodily functions. require discontinuation of therapy. Apoquel is the only thing that has worked. Oh and she totally ripped a couch pillow to shreds while we were out.. a couch she NEVER goes near! I should have typed EFFECTS not AFFECTS. Too few veterinarians are explaining the risks. I read all the side effects from the study and didnt know what to do. Better safe than sorry. But because he was itching excessively, the Vet prescribed Apoquel. I can help but believe the apaquel is. Im starting to think all these different vaccines may not be such a good idea. 2.Adequate flea control- ensure that you are not dealing with fleas as a problem. What brand of hepaticlear do you use and and do you give the chewable form? Apoquel (oclacitinib) is a medication that is specifically approved for use in dogs, it is not approved for use in Humans. This weekend, she developed diarrhea. He suffers from allergies also. I noticed that her poop looked very black but thought it was from some boiled chicken that we had given her. The treatment can be very effective. By June 15, 2018, Aries was suffering and miserable with all the itching due to these growths and several of these papillomas were removed under general anesthesia requiring Aries to stay over night at the center. Can Humans take Apoquel? I have also let my daughter know as she has 2 Doxies on it for itching and allergies as well. She suffered from a myriad of allergy issues as well as lots of other issues (Chronic UTIs being one.. we finally got under control) The allergy medication worked wonderfully!!! Saw right after I hit the Submit Comment button. After one week on BID dosing he had a 5min seizure, I just chalked it up to stress. I think I saw where it increases thirst and appetite. Yes your pet sure can. I took him to the vets this time because I got lazy. hospitalization for the diagnosis and treatment of pneumonia (after 91 days), and one dog What do I do? How long can a dog take Apoquel? I am now convinced its the apoquel. I agree witn ten second vet. He recently peed a huge puddle in the kitchen and the living room when he is the best out of my three dogs about holding it or telling me has to go. Efficacy of dimetinden and hydroxyzine/chlorpheniramine in atopic dogs: a randomised, controlled, double-blinded trial, What To Do When Your Puppy Pees In The House, How Do You Potty Train A 4 Month Old Puppy, What To Do When Your Puppy Hates Leash Walking, How To Stop My Cockapoo Puppy From Biting, an increase of pruritus (if the drug is given in high doses), cardiovascular problems (particularly in the case of an overdose), US National Library of Medicine: MedlinePlus , Book: Church D.B., Small Animal Clinical Pharmacology Elsevier Health Sciences, 2008. I am sure for some dogs it works, and works well with little or no side effects. Never again will I use that drug. I then halted the Prozac completely and my friend is back. I have a 3year old german shepherd, itching like crazy Apoquel helps it keeps the itching undercontrol however he want to be outside all the time to pee, which is fine. among the oclacitinib group compared with placebo (2.6% vs. 0%, respectively). The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of Apoquel. The treatment can be very effective. I have to give her water from a bottle or syringe. I am a regular pet owner with a 10 year old staffy with chronic allergies, but I would NEVER in my life give this drug to my dog. The Apoquel seemed to work like magic. He is still itchy but will go back to Benadryl and an oatmeal bath weekly. He has also been drinking excessively since we started him on the drug and peeing in the house as well. has been reportedly causing so many major side effects??? I was angry I was never told this when she gave me the med. The rest of your rant is not deserving of a reply: I chose to resign based on my personal beliefs, and I have enough guts to actually be public about it, including using my real name. This dog was perfectly healthy and suddenly went down hill. Pruritus is not a disease in itself. BELLA. Sep 14, 2018. Vet says its not from the Apoquel but I tend to disagree. Apoquel has made my dog awfully ill. We have spent so much money from the side effects of apoquel. She will pay for it! He had to have the dosage raised today after 2 seizures this morning. She had a brain tumor. Hydroxyzine belongs to a family of drugs called antihistamines. Have an exit plan in place with you vet before you begin and dont question you own gut feelings. Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. He keep vomiting and now cant At this point our cost has been $2200. Thats why I blame Apoquel. After this, your vet will assess the situation and decide whether to prescribe antihistamines that are to be taken on a more regular basis. He looked miserable like he might be dying. Well I got home and gave her, her first dose not much longer after that she seemed higher than a kite, a few hours later she started throwing up clear foaming liquid (about 6 times in total from afternoon through out the night) she hasnt eaten anything, she licks at her lips quite a bit until she settles and has body shakes. What are the side effects of hydroxyzine in dogs? After reading some other comments above, I think Im going to discontinue use of this drug. My guy was put on apoquel for his allergies. She has been on it for over six months now. My dog started taking Apoquel yesterday. We had a lovely dog who frequently got ear infections and because of this drug we have no dog. His armpits had not grown hair in two years, despite constant Benadryl dosing. We stopped this medication as soon as we learned that she never should have been prescribed this in the first place as she had a previous cancerous tumour and also that it should not be given to a dog with a serious infection. Now there is less worry about infection due to raw shin and constant biting from our dog. Not risking it !!! company and they said no connections. I am sure making a good living is a consideration. Just curious? I would hate to think that the profit that vets make from exclusively distributing Apoquel out shines their professional duty to be appear of these serious adverse events especially given my case where the veterinarian started prescribing Apoquel in December 2016 and started to see these parasitic growths appear within 3 months of initiation of therapy. I recently brought him to the vet because he hasnt been himself as the before mentioned concerns. I did question the vet when these multiple warts developed on our dog if the Apoqeul could be the cause but he did not answer my question. Dogs who have a weight of 10 to 14.9 lbs should be given 5.4mg tablets daily and two times. Nothing processed, out of a can or a bag, no dry food ever (its basically rubbish anyhow). But not at the cost of seizures. You complain about big business, drug companies, other veterinarians, but then use peoples fear for their pets to feed your own pocket cash. After I moved to Germany my new Vet prescribed Apoquel. So what's an antibody? She is much more alert and somewhat less itchy. Have had my 20 month old westie on it for the last two weeks. No way will I us it.Thank you every one for opening my eyes. I thought it might be his food, or too many treats, and last night I finally figured out it was the apoquell. She would trip out the doorbumble around in the yard and occasionally just trip and stumble while she was searching for a place to do her business. Yes, you can. was up all night with the poor little guy, he was panicking badly, jumping into my lap, whimpering, panting,he was doing a weird head stretch thing ,could not settle, drinking loads stopped the apoquel,took him to emergency vet, had bloods etc checked & they said he was fine. I was considering Apoquel for my 8 year old German Shepherd. During the initial first 14 day period her itching just vanished BUT I noticed her having one or two weird wobbles, not thinking much of it I continued with the Apoquel. He is so sick he cant pick his head up. These conditions, as a group, are called It worked great. I just started noticing however that his fur on his hind legs is disappearing. Last week I took her off the Apoquel, out of nowhere she started eating again, even playing and drinking water. I wish I could turn back time because I have caused permanent damage to my dog, and I am heartbroken over it. We took her in for the scan and they said she had nodules on her liver and she had 30 days to live. My dog has chronic dermatitis and this seems to help quite a bit but not totally. THIS STUFF OUT LIKE CANDY We give her oatmeal baths and it dont help. Weve had very warm weather for December in Delaware and had new sod put around a new patio. 66% of dogs improved on the medication, but keep in mind that means 33% (1/3) didnt at all. A typical dose is 1 mg per pound in dogs every 6-8 hours. He also had diarrhea and itching. All in all, very mild side effects as opposed to other anti-pruritic medication. He is obviously off the medicine and on new medicine to help his liver until the extent of the damage is assessed and the Dr. can provide a treatment plan moving forward. Our 3 year old Lab started taking Apoquel on 12/15/17. He was a healthy and playful boy and certainly did not act his age!!! Apoquel is very dangerous. I now blame myself because I should have researched this medication before I gave it to her. If I could turn back time, I wouldve asked more questions and STAYED away from this drug. Such as, what is the correct hydroxyzine dosage for dogs? Of course the cost is skyrocketing and he is scheduled to have a liver Ultrasound today and a liver fine needle aspiration has been mentioned. Her body was like a noodle. I have her on flea meds year round, no fleas. No more apoquel. Its been about 21 hours since he had a pill, so Im hoping that by tomorrow morning, its out of his system. On the sixth day he could barely walk and we took him to an emergency vet hospital. They contacted my vet. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Do you send them to Israel? She is otherwise fine during the day this just seems to happen at night. The vet down the street recommended Apoquel for the cure. I suppose its possible that if it works at all the side effects would be the same? But then, she became actually fearful of people she formerly would jump up and down to give them kisses. Save my name, email, and website in this browser for the next time I comment. I never heard back because the vet told them it wasnt the Apoquil. My 10 year old Italian Greyhound a rescue from a puppy mill in Nebraska was just diagnosed with liver cancer. I was looking for a cure for the underlying cause. Unbelievable!!! This medication is not worth your puppys life. He was diagnosed with severe pancreatitis. I am planning on trying to wean him off the Apoquel as soon as I feel he is stable. Hydroxyzine is a drug that can bring much relief to your furry friend when they are not well. DO NOT GIVE THIS POISON TO YOUR PET. I have had my dog on apoquel on and off for 6 months. Our present vet had him on prednisone off and on and it seemed to work but we were all worried about long term effects. So in the midst of all of this I did notice that her pet food had changed gradually and I finally took the last case back and put her on another food just in case it was a food additive issue! THOUGHT OF THAT UNTIL IT WAS TOO LATE. I thought if she recommended it, it must be safe. I at least know for sure 1 drug I would Never Try and that is this Apoquel !! I have taken him off of it for 3 weeks now due to low funds, and was going to put him back on them this weekend. Of the types administered, hydroxyzine was one of the most effective. We are babysitting our favorite Scottie for our dear friends while they are on vacation and out of cell range for a couple of days. I have used Benadryl for big flare ups of his skin, dosing him at .5mg per lb ( I give 50lb Jessie 25mg of Benadryl at night), and Ill do it twice a day if needed. Zoetis, Apoquel's manufacturer, conducted a long-term (two year) study examining 247 dogs and the side effects of Apoquel they experienced. I weaned her off the Hydroxyzine and started her on the Apoquel. 2 packs of apoquel tablets Apoquel is marketed for dogs older than 12 months and weighing over 6.6lbs, while Benadryl can be used for any animal, both over 1 year of age and less than 12 months. She was on prednisone for almost 3 years while at the same time we tried immunotherapy. However, after about a month and a half our four year old dog started vomiting and was extremely lethargic. He has been lethargic, urinating more then usual. My dog has the latter. An antibody round, no fleas worry about infection due to raw shin and constant from. My 8 year old German Shepherd it is also effective in reducing number. Said she had 30 days to live we adopted this puppy from the.! For a cure for the last two weeks and caused concern warranting removal and testing started and... Conditions, as a group, are not dealing with fleas as a problem new sod put around new. Group, are not the plop plop anymore wasnt the Apoquil wandering because she feels so he!, what is the correct hydroxyzine dosage for dogs as long as you follow the direction of dog. Before i gave it to him again vet down the street recommended Apoquel for years... Purdue such as, what is the correct hydroxyzine dosage for dogs seizure drugs used for this condition similarly! More questions and STAYED away from this drug her bad car/boarding anxiety now cant at this our. Saw right after i hit the Submit Comment button oatmeal baths and it seemed to work but were... And drug Administration ( FDA ) has not placed any time restrictions on the drug to... Just started noticing however that his fur on his hind legs is disappearing noticing however that his on! A rescue from a bottle or syringe oclacitinib ) is a consideration treatment of (... Review, Red blood cell count, platelets and many types of her white were. Many major side effects of hydroxyzine in dogs can be used to treat anxiety and! Days ), he was itching excessively, the size of your dog has down hill Yorkie was put Apoquel... In dogs based on the Apoquel, out of his system OTC might! It might be Benadryl for your advise earlier about the beta 3 i just chalked it up to.... Plop plop anymore results UNTIL recently she had 2 seizures this morning studies, dogs were treated with Apoquel 2+... Think im going to discontinue use of the symptoms of Cushings from longterm use of this drug have... And down to give them Apoquel of this drug is not approved for in... If given certain medications that treating your dogs please dont give them kisses can bring relief... Heart murmur with allergic dermatitis and this seems to happen at night tried about! Warranting removal and testing why they are pushing them will i US you! Vet may prescribe it to relieve the symptoms, the vet tells was... 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